Clinical evaluation of the role of tulsi and turmeric in the management of oral submucous fibrosis: A pilot, prospective observational study
نویسندگان
چکیده
The aim of the present study was to investigate the clinical efficacy of herbal medicines (1 gm tulsi and 1 gm turmeric mixed in glycerine base) for the treatment of oral submucous fibrosis (OSMF). Forty-one patients in the age group of 17- 56 years without any systemic complications were included in the study. The patients were treated with medicines, which were to be applied 3-4 times a day. Blood samples were collected before and after treatment to screen for any systemic changes due to these medications. Burning sensation and mouth opening were recorded before and after treatment. Patients were followed up on monthly subsequent visits for three months. Changes in the burning sensation on visual analogue scale (VAS) scale and difference in the mouth opening were analyzed statistically. A statistically significant improvement was seen in both burning sensation and mouth opening. Tulsi and turmeric offers a safe and efficacious combination of natural products available for symptomatic treatment of OSMF.
منابع مشابه
A Review of Oral Submucousal Fibrosis, Related Factors, Prognosis and New Therapeutic Approaches
Abstract BACKGROUNackground and AIMD & AIM: Oral Submucous Fibrosis (OSF) is an oral premalignant condition with highest premalignant potential among oral precancerous lesions which characterized with inflammation and progressive fibrosis of submucosal oral tissues (cause to significant irreversible rigidity and trismus). During the years, many classification systems have been propo...
متن کاملComparative Study of Clinical Staging of Oral Submucous Fibrosis with Qualitative Analysis of Collagen Fibres Under Polarized Microscopy
Background & Objectives: Oral submucous fibrosis (OSMF) is a condition where excessive deposition of dense collagen fibers occurred in the connective tissue of oral mucosa. An alteration of collagen necessitates an in depth understanding of collagen in oral tissues as no breakthrough studies have been reported. Therefore the aim was to correlate the clinical, functional and histopathol...
متن کاملOral Submucous Fibrosis: A Chronic Deliberating Disease of Oral Cavity
Oral submucous fibrosis is chronic progressive condition of oral cavity. The condition is well recognized for its malignant potential. Usually the disease initiates with redness, blistering, and ulceration inside the mouth. It is characterized by progressive fibrosis of submucosal tissue. The pathogenesis of oral submucous fibrosis is not well understood. Betelquid chewing is the major etiologi...
متن کاملHistochemical and Immunohistochemical Analysis of Collagen Fibers and Microvascular Density in Various Grades of Oral Submucous Fibrosis
Background and Objective: This study was aimed to evaluate the collagen fibers qualitatively and its correlation with microvascular density in various grades of oral submucous fibrosis (OSMF). Material and Methods: The present study comprised of total 40 cases of oral submucous fibrosis. Picrosirius red staining was done on all the specimens’ sections. ...
متن کاملOral Submucous Fibrosis: a case report
We describe an interesting case of oral sub mucous fibrosis accompanied by severe trismus in a 23 years old man. The patient had initially been diagnosed as having internal derangement of the temporomandibular joint and conservative treatment had failed to decrease the symptoms. Despite extremely limited temporomandibular joint movement, cone beam computed tomography revealed no important abnor...
متن کامل